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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
38.48
Human Site:
Y177
Identified Species:
70.56
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
Y177
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
Y172
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
Y175
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Dog
Lupus familis
XP_543240
206
23431
K150
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
Y178
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Rat
Rattus norvegicus
P23441
372
38536
Y214
I
W
F
Q
N
H
R
Y
K
M
K
R
Q
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
Y464
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Chicken
Gallus gallus
Q90788
294
33054
Y172
I
W
F
Q
N
R
R
Y
K
C
K
R
Q
R
Q
Frog
Xenopus laevis
Q9W7E8
213
24704
T157
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
A
T
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Y178
I
W
F
Q
N
H
R
Y
K
M
K
R
A
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
Y228
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
Y203
I
W
F
Q
N
H
R
Y
K
C
K
R
Q
E
K
Sea Urchin
Strong. purpuratus
Q26656
405
44721
N306
I
W
F
Q
N
R
R
N
K
W
K
R
Q
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
100
100
6.6
N.A.
100
66.6
N.A.
100
73.3
13.3
66.6
N.A.
93.3
N.A.
66.6
66.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
73.3
N.A.
100
86.6
33.3
73.3
N.A.
100
N.A.
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
8
85
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% H
% Ile:
85
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
8
93
8
93
8
47
0
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
39
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
0
% M
% Asn:
0
0
8
8
85
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
85
0
0
0
0
0
0
0
8
39
47
8
% Q
% Arg:
0
0
0
8
16
70
85
0
0
8
8
85
0
16
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
47
0
0
0
0
16
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
85
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _